1. What is Rituximab Dose Calculation?

Rituximab is typically dosed at 375 mg/m² of body surface area (BSA) for many indications. This calculator computes the exact dose based on the patient's BSA.

2. How Does the Calculator Work?

The calculator uses the standard Rituximab dosing formula:

Where:

• 375 mg/m² — Standard Rituximab dose per square meter
• BSA — Body surface area in square meters

Explanation: The calculation multiplies the standard dose per square meter by the patient's actual body surface area.

3. Importance of Accurate Dosing

Details: Precise dosing based on BSA ensures optimal therapeutic effect while minimizing side effects. Underdosing may reduce efficacy, while overdosing increases toxicity risk.

4. Using the Calculator

Tips: Enter the patient's BSA in m² (must be >0). The result will be the total Rituximab dose in milligrams.

5. Frequently Asked Questions (FAQ)

Q1: How is BSA typically calculated?
A: BSA is commonly calculated using formulas like DuBois or Mosteller, based on height and weight.

Q2: Does this dose apply to all Rituximab indications?
A: While 375 mg/m² is standard for many uses, always confirm the dosing regimen for specific indications.

Q3: How often is this dose administered?
A: Frequency depends on the treatment protocol, often weekly for 4-8 doses in initial therapy.

Q4: Are there maximum dose limits?
A: Some protocols specify maximum doses (e.g., 1000 mg per dose) regardless of calculated dose.

Q5: How should the dose be rounded for administration?
A: Typically rounded to the nearest 10 mg or according to vial sizes available (100 mg/10 mL or 500 mg/50 mL vials).