Cornell Glucose Infusion Calculator

Glucose Infusion Rate (GIR) Equation:

\[ GIR = \frac{\text{Infusion Rate (mL/hr)} \times \text{Dextrose Concentration (g/dL)} \times 1000 \text{ (mg/g)}}{\text{Weight (kg)} \times 60 \text{ (min/hr)} \times 100 \text{ (mL/dL)}} \]

Glucose Infusion Rate (GIR):

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1. What is Glucose Infusion Rate (GIR)?

The Glucose Infusion Rate (GIR) measures how quickly glucose is being administered to a patient, expressed in mg/kg/min. It's commonly used in neonatal and pediatric intensive care to monitor and adjust intravenous glucose administration.

2. How Does the Calculator Work?

The calculator uses the GIR equation:

\[ GIR = \frac{\text{Infusion Rate} \times \text{Dextrose Concentration} \times 1000}{\text{Weight} \times 60 \times 100} \]

Where:

Infusion Rate — IV fluid administration rate (mL/hr)
Dextrose Concentration — Percentage of dextrose in solution (g/dL)
Weight — Patient's weight in kilograms (kg)
1000 — Conversion factor (mg/g)
60 — Conversion factor (min/hr)
100 — Conversion factor (mL/dL)

Explanation: The equation converts the infusion parameters into a standardized rate of glucose administration per kilogram of body weight per minute.

3. Importance of GIR Calculation

Details: Accurate GIR calculation is crucial for maintaining appropriate glucose levels in patients receiving IV therapy, especially in neonates and critically ill patients where precise glucose control is essential.

4. Using the Calculator

Tips: Enter the infusion rate in mL/hr, dextrose concentration in g/dL (e.g., 10% dextrose = 10 g/dL), and patient weight in kg. All values must be positive numbers.

5. Frequently Asked Questions (FAQ)

Q1: What is a typical GIR range for neonates?
A: Term neonates typically start at 4-6 mg/kg/min, while preterm infants may start at 6-8 mg/kg/min, adjusted based on glucose monitoring.

Q2: How does GIR relate to blood glucose levels?
A: Higher GIR generally leads to higher blood glucose levels, but individual responses vary based on insulin sensitivity and metabolic state.

Q3: When should GIR be adjusted?
A: GIR should be adjusted based on frequent blood glucose monitoring, especially in patients with unstable glucose metabolism.

Q4: Are there limitations to GIR calculation?
A: GIR doesn't account for endogenous glucose production or utilization, so clinical correlation with blood glucose measurements is essential.

Q5: How is GIR used in TPN management?
A: In total parenteral nutrition (TPN), GIR helps ensure appropriate glucose delivery while minimizing the risk of hyperglycemia or hypoglycemia.