Glucose Infusion Rate Calculator Cornell University

Glucose Infusion Rate (GIR) Formula:

\[ GIR = \frac{\text{Infusion Rate (mL/hr)} \times \text{Dextrose Concentration (g/dL)} \times 1000 \text{ (mg/g)}}{\text{Weight (kg)} \times 60 \text{ (min/hr)} \times 100 \text{ (mL/dL)}} \]

Glucose Infusion Rate (GIR):

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1. What is Glucose Infusion Rate (GIR)?

The Glucose Infusion Rate (GIR) measures the rate at which glucose is being administered to a patient, expressed in milligrams per kilogram per minute (mg/kg/min). It's particularly important in neonatal and pediatric intensive care settings to ensure appropriate glucose delivery.

2. How Does the Calculator Work?

The calculator uses the GIR formula:

\[ GIR = \frac{\text{Infusion Rate} \times \text{Dextrose Concentration} \times 1000}{\text{Weight} \times 60 \times 100} \]

Where:

Infusion Rate — Rate of IV fluid administration (mL/hr)
Dextrose Concentration — Percentage of dextrose in solution (g/dL)
1000 — Conversion factor (mg/g)
Weight — Patient's weight in kilograms (kg)
60 — Conversion factor (min/hr)
100 — Conversion factor (mL/dL)

Explanation: The equation converts the infusion parameters into a standardized measure of glucose delivery per unit of body weight per minute.

3. Importance of GIR Calculation

Details: Accurate GIR calculation is crucial for maintaining appropriate glucose levels in critically ill patients, especially neonates, to prevent both hypoglycemia and hyperglycemia.

4. Using the Calculator

Tips: Enter the IV infusion rate in mL/hr, dextrose concentration in g/dL (e.g., 10 for D10W), and patient weight in kg. All values must be positive numbers.

5. Frequently Asked Questions (FAQ)

Q1: What is a typical GIR range for neonates?
A: For term neonates, initial GIR is typically 4-6 mg/kg/min, adjusted based on blood glucose monitoring.

Q2: How does GIR relate to blood glucose levels?
A: GIR provides the glucose input, but actual blood glucose depends on endogenous production, utilization, and insulin activity.

Q3: When should GIR be calculated?
A: Whenever dextrose-containing IV fluids are administered, especially in neonates, pediatric patients, or critical care settings.

Q4: Are there limitations to GIR calculation?
A: GIR doesn't account for oral intake or endogenous glucose production. Clinical judgment and glucose monitoring are essential.

Q5: How to adjust GIR for hypoglycemia or hyperglycemia?
A: Adjust either the infusion rate or dextrose concentration while monitoring blood glucose response.