1. What is Rituxan Rate Calculation?

Rituxan (rituximab) infusion rates must be carefully controlled to minimize infusion reactions. The standard protocol starts at 50 mg/hr with incremental increases every 30 minutes up to a maximum of 400 mg/hr.

2. How Does the Calculator Work?

The calculator follows the standard Rituxan administration protocol:

The calculator determines:

• Current infusion rate based on infusion number
• Next recommended rate (if applicable)

3. Importance of Proper Infusion Rates

Details: Gradual rate escalation helps prevent infusion-related reactions which can include fever, chills, rigors, hypotension, and rarely severe reactions including cardiac arrest.

4. Using the Calculator

Tips: Enter the initial rate (typically 50 mg/hr) and the current infusion number (1-8). The calculator will show the current rate and next recommended rate.

5. Frequently Asked Questions (FAQ)

Q1: Can the initial rate be higher than 50 mg/hr?
A: Only in special circumstances with physician approval and close monitoring.

Q2: What if the patient tolerates the infusion well?
A: The rate should still follow the standard escalation protocol to minimize risk of delayed reactions.

Q3: How long does the full infusion take?
A: Typically 4-6 hours for the first infusion, shorter for subsequent infusions if tolerated.

Q4: What monitoring is required during infusion?
A: Vital signs should be monitored before infusion, at each rate increase, and at completion.

Q5: What if the patient has a reaction?
A: The infusion should be stopped and appropriate medical management initiated.