IT Ratio Formula:
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The IT (Indirect/Total) Ratio is a calculation used in neonatal care to assess the proportion of indirect bilirubin in the total bilirubin level. This ratio helps in evaluating neonatal jaundice and determining appropriate treatment approaches.
The calculator uses the IT Ratio formula:
Where:
Explanation: The IT Ratio helps differentiate between different types of hyperbilirubinemia in newborns, which is crucial for proper management.
Details: In NICU settings, the IT Ratio is particularly important for:
Tips:
Q1: What is a normal IT Ratio in newborns?
A: Typically >75% is considered normal for indirect hyperbilirubinemia. Values below 20% suggest predominantly direct hyperbilirubinemia.
Q2: When is IT Ratio most useful?
A: It's particularly helpful in evaluating jaundice in the first week of life and in cases where hemolytic disease is suspected.
Q3: How does IT Ratio affect treatment decisions?
A: Higher IT Ratios may indicate a greater need for phototherapy, while low ratios may suggest biliary obstruction or other conditions requiring different interventions.
Q4: Are there limitations to IT Ratio interpretation?
A: Yes, the ratio should always be interpreted in clinical context along with other lab values and physical examination findings.
Q5: How often should IT Ratio be monitored?
A: Frequency depends on the clinical situation, but typically every 6-12 hours in cases of significant hyperbilirubinemia or when treatment is initiated.