1. What is IVIG Rate Calculation?

The IVIG (Intravenous Immunoglobulin) rate calculation determines the appropriate infusion rate based on the prescribed dose per kilogram per minute and the patient's weight. This ensures safe and effective administration of IVIG therapy.

2. How Does the Calculator Work?

The calculator uses the IVIG rate equation:

Where:

• \( Dose \) — Prescribed IVIG dose in mg per kg per minute
• \( Weight \) — Patient's weight in kilograms
• \( 60 \) — Conversion factor from minutes to hours

Explanation: The equation converts the weight-based dose from mg/kg/min to the total mg/hr infusion rate.

3. Importance of IVIG Rate Calculation

Details: Proper IVIG infusion rate calculation is essential to prevent adverse reactions while ensuring therapeutic effectiveness. Rates that are too fast may cause infusion reactions.

4. Using the Calculator

Tips: Enter the prescribed dose in mg/kg/min and the patient's weight in kg. Both values must be positive numbers.

5. Frequently Asked Questions (FAQ)

Q1: What are typical IVIG infusion rates?
A: Rates vary by protocol but often start at 0.5-1 mg/kg/min, gradually increasing based on tolerance to 2-4 mg/kg/min.

Q2: Why is weight important in IVIG dosing?
A: IVIG is dosed based on ideal body weight to avoid overdosing in obese patients and ensure adequate dosing in underweight patients.

Q3: What factors might require rate adjustment?
A: Patient tolerance, history of reactions, renal function, and concurrent conditions may necessitate slower rates.

Q4: How often should vital signs be monitored during infusion?
A: Typically every 15-30 minutes during initial infusions, then hourly once stable, with more frequent monitoring if rate increases.

Q5: What are signs of infusion reaction?
A: Fever, chills, headache, nausea, flushing, chest tightness, or changes in blood pressure may indicate a reaction requiring rate reduction.